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WRN

Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN,RECQ3, RECQL2

Catalog Number:
E2309T-H07H
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Description:Recombinant human WRN protein with N-terminal 6x His tag was purified by Ni-NTA affinity and followed by SEC chromatography. The WRN protein showed high activity in FI assay.


Species:Human


Tag:N-terminal 6x His tag


Expression Host:HEP sf9


Uniprot:Q14191


Sequences:M1-I333


Molecular Weight:40.2 kDa


Formulation:50 mM Tris, 150 mM NaCl, 1 mM DTT, 10% glycerol, pH7.5


Form:Liquid


Purity:> 95% 


Stability&Storage:Stable for 12 months upon stored at -80℃ from the date of receipt. And avoid repeated freeze-thaws cycles.


SDS-PAGE:

  13.胶图WRN.png


Activity Identification:The WRN exonuclease activity detected by FI technology. The reaction was performed by incubating the WRN protein, ATP and dsDNA at 25℃ for 60 min, then reading the ratio 320/360 with BMG.

13.WRN-1.png13.WRN-2.png

Note:

1. This product is for research use only. Do not use for medical, clinical diagnosis or treatment, food, or cosmetic purposes. Do not store in residential areas.

2. For your safety and health, please wear lab coats and disposable gloves and masks when handling.

3. Experimental results may be influenced by various factors. Related handling is limited to the product itself and does not involve other compensations.

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