EGFR[d746-750/T790M/C797S]

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Epidermal growth factor receptor, ERBB, ERBB1, HER1

Catalog Number:

S2506T-H05

Size：

10 μg 100 μg 1 mg

COA:

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Product Information
Routine QC
Activity Identification

Description：Recombinant human EGFR[d746-750/T790M/C797S] protein with N-terminal GST tag was purified by GST affinity, the GST tag was subsequently removed. The EGFR[d746-750/T790M/C797S] protein showed high activity in HTRF assay.

Species：Human

Tag：No Tag

Expression Host：HEP sf9

Uniprot：P00533-1

Sequences：G696-G1022[d746-750/T790M/C797S]

Molecular Weight：36.7 kDa

Formulation：25 mM Tris, 100 mM NaCl, 1 mM DTT, 0.05% Brij35, 10% glycerol, pH7.5

Form：Liquid

Purity：>60%

Stability&Storage：Stable for 12 months upon stored at -80℃ from the date of receipt. And avoid repeated freeze-thaws cycles.

SDS-PAGE：

G150904021-EGFR[d746-750 T790M C797S].pn

Activity Identification：The EGFR[d746-750/T790M/C797S] activity was quantified using a HTRF-based assay. The reaction was performed by incubating the EGFR[d746-750/T790M/C797S] protein, ATP and substrate at 25℃ for 60 min, then adding the donor and receptor, and keeping the mixture at 25℃ for 60 min, finally measuring the 665nm/620nm fluorescence signal ratio on BMG.

G150904021-EGFR[d746-750 T790M C797S].pn

Note：

1. This product is for research use only. Do not use for medical, clinical diagnosis or treatment, food, or cosmetic purposes. Do not store in residential areas.

2. For your safety and health, please wear lab coats and disposable gloves and masks when handling.

3. Experimental results may be influenced by various factors. Related handling is limited to the product itself and does not involve other compensations.